A basophil-neuronal axis promotes itch
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2020.12.033
Abstract: Itch is an evolutionarily conserved sensation that facilitates expulsion of pathogens and noxious stimuli from the skin. However, in organ failure, cancer, and chronic inflammatory disorders such as atopic dermatitis (AD), itch becomes chronic, intractable,… read more here.
Keywords: acute itch; itch; axis promotes; basophil neuronal ... See more keywords
An HLA-G/SPAG9/STAT3 axis promotes brain metastases
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2205247120
Abstract: Significance Current treatment options for Brain Metastases (BM) still result in reduced survival outcomes in affected patients, emphasizing the need for a better understanding of the disease and consequently more efficient therapies. In this study,… read more here.
Keywords: spag9 stat3; brain metastases; brain; stat3 axis ... See more keywords
The IL-33/ST2 axis promotes ARDS by killing natural T cells.
Sign Up to like & getrecommendations! Published in 2023 at "Shock"
DOI: 10.1097/shk.0000000000002114
Abstract: ABSTRACT Acute respiratory distress syndrome (ARDS) is characterized by uncontrolled inflammation, which manifests as leukocyte infiltration and lung injury. However, the molecules that initiate this infiltration remain incompletely understood. We evaluated the effect of the… read more here.
Keywords: lung injury; lung; mice; axis promotes ... See more keywords
The IL-4/IL-13 signaling axis promotes prostatic fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0275064
Abstract: Background Lower urinary tract symptoms (LUTS) are a costly and pervasive medical problem for millions of aging men. Recent studies have showed that peri-urethral tissue fibrosis is an untreated pathobiology contributing to LUTS. Fibrosis results… read more here.
Keywords: expression; pro fibrotic; peri urethral; fibrosis ... See more keywords