HPA axis regulation and epigenetic programming of immune-related genes in chronically stressed and non-stressed mid-life women
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.11.027
Abstract: Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been associated with altered immune function, but the underlying molecular mechanisms are unclear. Epigenetic processes, including DNA methylation, respond to the glucocorticoid end-products of the HPA axis (cortisol in humans)… read more here.
Keywords: chronically stressed; methylation; axis regulation; hpa axis ... See more keywords
Urbanicity, behavior problems and HPA axis regulation in preschoolers
Sign Up to like & getrecommendations! Published in 2022 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2022.105660
Abstract: Growing up in cities is associated with increased risk for developing mental health problems. Stress exposure and altered stress regulation have been proposed as mechanisms linking urbanicity and psychopathology, with most research conducted in adult… read more here.
Keywords: axis regulation; behavior problems; urbanicity behavior; hpa axis ... See more keywords
Sources, Processing-Related Transformation, and Gut Axis Regulation of Conventional and Potential Prebiotics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00168
Abstract: One strategy to achieve a balanced intestinal microbiota is to introduce prebiotics. Some substances present in the diet, such as soybean extracts, koji glycosylceramides, grape extracts, tea polyphenols, and seaweed extracts, can be considered as… read more here.
Keywords: axis regulation; gut axis; potential prebiotics; transformation ... See more keywords
Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress
Sign Up to like & getrecommendations! Published in 2017 at "Nature Neuroscience"
DOI: 10.1038/nn.4491
Abstract: The hypothalamic–pituitary–adrenal axis is a pivotal component of an organism's response to stressful challenges, and dysfunction of this neuroendocrine axis is associated with a variety of physiological and psychological pathologies. We found that corticotropin-releasing factor… read more here.
Keywords: essential hpa; hpa axis; crfr1 essential; axis regulation ... See more keywords
The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2019.00515
Abstract: The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune… read more here.
Keywords: regulation mood; axis regulation; mood disorders; neuroimmune axis ... See more keywords
The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10050791
Abstract: The NRF2/KEAP1 pathway is a fundamental signaling cascade that controls multiple cytoprotective responses through the induction of a complex transcriptional program that ultimately renders cancer cells resistant to oxidative, metabolic and therapeutic stress. Interestingly, accumulating… read more here.
Keywords: regulation tumor; keap1 axis; nrf2 keap1; tumor metabolism ... See more keywords