Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation.
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DOI: 10.1016/j.ydbio.2020.05.010
Abstract: The Dishevelled proteins transduce both canonical Wnt/β-catenin and non-canonical Wnt/planar cell polarity (PCP) signaling pathways to regulate many key developmental processes during embryogenesis. Here, we disrupt both canonical and non-canonical Wnt pathways by targeting the… read more here.
Keywords: dvl tko; canonical wnt; axis specification; differentiation ... See more keywords