Abstract 1033: Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1033
Abstract: Pancreatic ductal adenocarcinoma (PDA) is characterized by an activating mutation in KRAS. Direct inhibition of KRAS through pharmacological means remains a challenge; however, targeting key KRAS effectors has therapeutic potential. We investigated the contribution of… read more here.
Keywords: axl; tbk1; axl mediated; cancer ... See more keywords
Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.126117
Abstract: Pancreatic ductal adenocarcinoma (PDA) is characterized by an activating mutation in KRAS. Direct inhibition of KRAS through pharmacological means remains a challenge; however, targeting key KRAS effectors has therapeutic potential. We investigated the contribution of… read more here.
Keywords: epithelial plasticity; axl; tbk1; mediated activation ... See more keywords