Articles with "axl vegfr2" as a keyword



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Preclinical characterization and phase I clinical trial of CT053PTSA targets MET, AXL, and VEGFR2 in patients with advanced solid tumors

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1024755

Abstract: Background CT053PTSA is a novel tyrosine kinase inhibitor that targets MET, AXL, VEGFR2, FLT3 and MERTK. Here, we present preclinical data about CT053PTSA, and we conducted the first-in-human (FIH) study to evaluate the use of… read more here.

Keywords: ct053ptsa; trial; met axl; phase ... See more keywords