Programmed axon death: a promising target for treating retinal and optic nerve disorders
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DOI: 10.1038/s41433-024-03025-0
Abstract: Programmed axon death is a druggable pathway of axon degeneration that has garnered considerable interest from pharmaceutical companies as a promising therapeutic target for various neurodegenerative disorders. In this review, we highlight mechanisms through which… read more here.
Keywords: retinal optic; programmed axon; axon death; optic nerve ... See more keywords
What Is the Role of Mitochondrial Dysfunction in Programmed Axon Death?
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200691
Abstract: Axonal loss occurs in many neurologic disorders and its prevention is a major target of disease-modifying therapies. Over the past several years, studies in the Wlds mutant mouse model characterized by delayed Wallerian degeneration (WD)… read more here.
Keywords: mitochondrial dysfunction; programmed axon; role mitochondrial; axon death ... See more keywords