Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats
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DOI: 10.1186/s12974-017-0805-x
Abstract: BackgroundAxon development plays a pivotal role in the formation of synapse, nodes of Ranvier, and myelin sheath. Interleukin-1β (IL-1β) produced by microglia may cause myelination disturbances through suppression of oligodendrocyte progenitor cell maturation in the… read more here.
Keywords: p38 mapk; microscopy; microglia derived; expression ... See more keywords