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Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.848257
Abstract: Nexmif is mainly expressed in the central nervous system (CNS) and plays important roles in cell migration, cell to cell and cell-matrix adhesion, and maintains normal synaptic formation and function. Nevertheless, it is unclear how…
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Keywords:
morphogenesis;
motor neurons;
morphogenesis motor;
axon morphogenesis ... See more keywords
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Published in 2017 at "eLife"
DOI: 10.7554/elife.25453
Abstract: The etiological underpinnings of amyotrophic lateral sclerosis (ALS) are complex and incompletely understood, although contributions to pathogenesis by regulators of proteolytic pathways have become increasingly apparent. Here, we present a novel variant in UBQLN4 that…
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Keywords:
als associated;
variant ubqln4;
novel als;
motor axon ... See more keywords
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Published in 2018 at "eLife"
DOI: 10.7554/elife.36374
Abstract: Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport, but the underlying mechanisms are not well understood. Here, we report our study of MAP7, a unique microtubule-associated protein that interacts with both microtubules and…
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Keywords:
map7;
organelle transport;
transport;
morphogenesis ... See more keywords