MTEP impedes the neuronal polarization and the activity of the Akt–NF‐κB pathway in rat hippocampal neurons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24002
Abstract: Metabotropic glutamate receptor 5 (mGluR5) is extensively involved in neural survival, differentiation, dendritic morphology, synaptic plasticity, and neural circuit formation. However, little is known about its role in neuronal polarization and axon outgrowth. In this… read more here.
Keywords: hippocampal neurons; axon outgrowth; mglur5; neuronal polarization ... See more keywords
CXCL1 and CXCL2 Inhibit the Axon Outgrowth in a Time- and Cell-Type-Dependent Manner in Adult Rat Dorsal Root Ganglia Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02861-x
Abstract: The ability to regrow their axons after an injury is a hallmark of neurons in peripheral nervous system which distinguish them from central nervous system neurons. This ability is influenced by their intrinsic capacity to… read more here.
Keywords: root ganglia; dorsal root; axon outgrowth; ganglia neurons ... See more keywords
TC10 on endosomes regulates the local balance between microtubule stability and dynamics through the PAK2-JNK pathway and promotes axon outgrowth.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of cell science"
DOI: 10.1242/jcs.263636
Abstract: The neuronal cytoskeleton comprises microtubules, actin filaments and neurofilaments, and plays a crucial role in axon outgrowth and transport. Microtubules and actin filaments have attracted considerable attention in axon regeneration studies. We have previously shown… read more here.
Keywords: tc10; promotes axon; stability dynamics; microtubule stability ... See more keywords
PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0193257
Abstract: Inhibition of the phospholipid phosphatase and tumor suppressor PTEN leads to excessive polarized cell growth during directed cell migration and neurite outgrowth. These processes require the precise regulation of both the actin and microtubule cytoskeleton.… read more here.
Keywords: axon outgrowth; suppresses axon; pten suppresses; detyrosinated microtubules ... See more keywords
Non-nutritive Sweeteners Induce Hypothalamic ER Stress Causing Abnormal Axon Outgrowth
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00876
Abstract: With the prevalence of obesity, non-nutritive sweeteners (NNS) have been widely used as sugar substitutes as they deliver a sweet taste without excessive caloric load. However, it is increasingly recognized that NNS are not inert… read more here.
Keywords: stress; non nutritive; axon outgrowth; acesulfame potassium ... See more keywords
Retrograde Ret signaling controls sensory pioneer axon outgrowth
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.46092
Abstract: The trafficking mechanisms and transcriptional targets downstream of long-range neurotrophic factor ligand/receptor signaling that promote axon growth are incompletely understood. Zebrafish carrying a null mutation in a neurotrophic factor receptor, Ret, displayed defects in peripheral… read more here.
Keywords: growth; pioneer; axon outgrowth; pioneer axon ... See more keywords