Rho signaling inhibitor, CCG-1423, inhibits axonal elongation and dendritic complexity of rat cortical neurons.
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DOI: 10.1016/j.bbrc.2017.08.071
Abstract: CCG-1423, a chemical inhibitor of Rho signaling, blocks serum response factor (SRF)/megakaryoblastic leukemia 1 (MKL1)-mediated gene expression by inhibiting the nuclear accumulation of MKL1. Several studies have suggested that CCG-1423 interacts not only with MKL1,… read more here.
Keywords: rho signaling; complexity; axonal elongation; ccg 1423 ... See more keywords