Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
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DOI: 10.1016/j.celrep.2021.109134
Abstract: SUMMARY Axonal generation of Alzheimer’s disease (AD)-associated amyloid-β (Aβ) plays a key role in AD neuropathology, but the cellular mechanisms involved in its release have remained elusive. We previously reported that palmitoylated APP (palAPP) partitions… read more here.
Keywords: endoplasmic reticulum; axonal generation; associated endoplasmic; generation ... See more keywords