Articles with "axonal outgrowth" as a keyword



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Elevated miR-29a Contributes to Axonal Outgrowth and Neurological Recovery After Intracerebral Hemorrhage via Targeting PTEN/PI3K/Akt Pathway.

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Published in 2020 at "Cellular and molecular neurobiology"

DOI: 10.1007/s10571-020-00945-9

Abstract: Spontaneous intracerebral hemorrhage (ICH) is a clinical challenge with high disability and lacks an effective treatment. miR-29a strongly expressed in the brain has been implicated in various neurological disorders. In this study, we investigated the… read more here.

Keywords: outgrowth neurological; mir 29a; outgrowth; pi3k akt ... See more keywords
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Matrilin-2 within a three-dimensional lysine-modified chitosan porous scaffold enhances Schwann cell migration and axonal outgrowth for peripheral nerve regeneration

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Published in 2023 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2023.1142610

Abstract: Background: Matrilin-2 is a key extracellular matrix protein involved in peripheral nerve regeneration. We sought to develop a biomimetic scaffold to enhance peripheral nerve regeneration by incorporating matrilin-2 within a chitosan-derived porous scaffold. We hypothesized… read more here.

Keywords: matrilin; axonal outgrowth; migration; peripheral nerve ... See more keywords
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DIP2B Interacts With α-Tubulin to Regulate Axon Outgrowth

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Published in 2020 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2020.00029

Abstract: Axonal development is essential to the establishment of neuronal morphology and circuitry, although the mechanisms underlying axonal outgrowth during the early developmental stages remain unclear. Here, we showed that the conserved disco-interacting protein B (DIP2B)… read more here.

Keywords: interacts tubulin; outgrowth; dip2b; dip2b interacts ... See more keywords
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Induction of Axonal Outgrowth in Mouse Hippocampal Neurons via Bacterial Magnetosomes

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22084126

Abstract: Magnetosomes are membrane-enclosed iron oxide crystals biosynthesized by magnetotactic bacteria. As the biomineralization of bacterial magnetosomes can be genetically controlled, they have become promising nanomaterials for bionanotechnological applications. In the present paper, we explore a… read more here.

Keywords: bacterial magnetosomes; hippocampal neurons; outgrowth; mouse hippocampal ... See more keywords