Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing
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DOI: 10.1038/s41467-019-09164-3
Abstract: GABAB receptors (GBRs) are key regulators of synaptic release but little is known about trafficking mechanisms that control their presynaptic abundance. We now show that sequence-related epitopes in APP, AJAP-1 and PIANP bind with nanomolar… read more here.
Keywords: formation; complex formation; gbr; axonal trafficking ... See more keywords