Synthesis of aza-BODIPY dyes bearing the naphthyl groups at 1,7-positions and application for singlet oxygen generation
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2019.02.016
Abstract: Abstract Using 2-vinylnaphthalene, aza-BODIPYs with the naphthyl groups at 1,7-positions were prepared and their photophysical properties were characterized. Due to attachment of the naphthyl groups at 1,7-positions, aza-BODIPYs show long-wavelength absorption and emission in the… read more here.
Keywords: singlet oxygen; groups positions; oxygen generation; aza bodipy ... See more keywords
Facile synthesis of dimeric aza-BODIPY analogues from electron-deficient bislactams and their intriguing optical and electrochemical properties
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.06.088
Abstract: Abstract Electron-deficient bislactams, isoindigo and benzodipyrrolidone, were converted into dimeric aza-BODIPY analogues by a Schiff base forming reaction. These novel aza-BODIPY analogues exhibited bathochromically-shifted absorption and anodic shifts of the reduction potentials, implying their potential… read more here.
Keywords: aza bodipy; electron deficient; bodipy analogues; deficient bislactams ... See more keywords
First Comparison Study of the In Vitro and In Vivo Properties of a Randomly and Site-Specifically Conjugated SPECT/NIRF Monomolecular Multimodal Imaging Probe (MOMIP) Based on an aza-BODIPY Fluorophore.
Sign Up to like & getrecommendations! Published in 2023 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.3c00080
Abstract: Among all approaches in molecular imaging, the combination of near-infrared fluorescence imaging (NIRF) with radioisotopic imaging (PET or SPECT) allows one to benefit from the advantages of each of the imaging techniques, which are very… read more here.
Keywords: bodipy fluorophore; based aza; aza bodipy; monomolecular multimodal ... See more keywords
Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c02154
Abstract: The discovery of novel photosensitizers with potent phototoxicity and desirable water solubility is an urgent task for photodynamic therapy. Herein, a series of amino acid-modified aza-BODIPY photosensitizers were synthesized and evaluated. These new PSs exhibited… read more here.
Keywords: photodynamic therapy; amino acid; discovery; acid modified ... See more keywords
Discovery of Subcellular-Targeted Aza-BODIPY Photosensitizers for Efficient Photodynamic Antitumor Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01653
Abstract: In this study, we linked classical organelle-targeting groups, such as triphenylphosphonium, pentafluorobenzene, and morpholine, to our previously reported potent monoiodo Aza-BODIPY photosensitizer (BDP-15). They were conveniently prepared and retained the advantages of Aza-BODIPY PS with… read more here.
Keywords: discovery subcellular; subcellular targeted; antitumor; targeting groups ... See more keywords
Aza-BODIPY Route to Ageladine A.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04307
Abstract: The marine natural product ageladine A was synthesized by exploiting novel aza-BODIPY-type boron complexes that allowed the regioselective dibromination of the pyrrole unit, as confirmed by quantum chemical calculation (ωB97XD/TApr-cc-pVDZ). The parent tricycle was accessed… read more here.
Keywords: aza bodipy; route ageladine; ageladine; bodipy route ... See more keywords
Synthesis of Aza-BODIPYs, Their Differential Binding for Cu(II), and Results of Bioimaging as Fluorescent Dyes of Langerhans β-Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04151
Abstract: Cellular labeling through the use of dyes is of great interest to the biomedical sciences for the characterization of the location and distribution of biomolecules and also for the tracking of the course of biological… read more here.
Keywords: synthesis aza; aza bodipys; synthesis; bodipys differential ... See more keywords
Near-infrared aza-BODIPY fluorescent probe for selective Cu2+ detection and its potential in living cell imaging.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt03481d
Abstract: A near-infrared (NIR) fluorescent sensor 1 composed of an aza-boron-dipyrromethene (aza-BODIPY) core covalently bound to two di-2-picolylamine moieties was conceived for Cu2+ detection in aqueous solutions. Spectroscopic properties and binding abilities with several metal ions… read more here.
Keywords: detection; near infrared; fluorescent; cu2 detection ... See more keywords
Near infra-red dyes based on pyrene aza-BODIPYs
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c7nj03408c
Abstract: Pyrene substituted donor–acceptor type NIR aza-BODIPYs were designed and synthesized. The 1,7-positions of the aza-BODIPY core were substituted by pyrene moieties and the 3,5-positions were substituted with phenyl/2-thienyl or anisyl groups in the aza-BODIPYs. The… read more here.
Keywords: bodipy core; aza bodipys; aza bodipy; bodipys ... See more keywords
Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra01948k
Abstract: A bivalent indomethacin/Aza-BODIPY conjugate can selectively visualize the COX-2 enzyme in cancer and inflamed cells confirming its potential as a COX-2-specific biomarker in clinical applications. read more here.
Keywords: visualization cyclooxygenase; selective visualization; cancer; aza bodipy ... See more keywords
An aza-BODIPY-based NIR-II luminogen enables efficient phototheranostics.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00670g
Abstract: The fabrication of a high-performance second near-infrared (NIR-II) biological window fluorophore is in urgent need for precise diagnosis and treatment of cancer. Nevertheless, the construction of phototherapeutic agents in the NIR-II region with excellent imaging… read more here.
Keywords: bodipy based; cb1 nanoparticles; cb1; based nir ... See more keywords