Abstract 5081: Disruption of DNA methyltransferase (DNMT) 1 confers resistance to DNMT inhibitors in human colorectal cancer cells
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DOI: 10.1158/1538-7445.am2017-5081
Abstract: DNA methyltransferase (DNMT) 1 is responsible for the maintenance and propagation of DNA methylation pattern, and plays an important role in cell survival and proliferation. Thus, targeting DNMT represents a promising approach for cancer treatment.… read more here.
Keywords: aza dcyd; dnmt; aza; dnmt1 ... See more keywords