Diastereoselective synthesis of highly substituted tetrahydroquinolines using benzoylacetonitrile via aza Diels–Alder reaction
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153063
Abstract: Abstract Diastereoselective aza-Diels–Alder reaction between in situ generated 2-aminophenyl-substituted enones and α-cyano-α,β-unsaturated aromatic ketone has been developed. In the presence of TEA as a catalyst prepared highly substituted tetrahydroquinolines with an all-carbon quaternary center in… read more here.
Keywords: aza diels; alder reaction; highly substituted; diels alder ... See more keywords
Mechanism, Stereoselectivity, and Role of O2 in Aza-Diels-Alder Reactions Catalyzed by Dinuclear Molybdenum Complexes: A Theoretical Study.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.2c00035
Abstract: The aza-Diels-Alder-type reaction between imines and functionalized alkenes is one of the most versatile approaches to obtain piperidine derivatives. When using the Lewis acid [Mo2(OAc)4] (CAT) as a catalyst, it was found that the activation… read more here.
Keywords: aza diels; stereoselectivity; reaction; diels alder ... See more keywords
Synthesis of Tris-Heterocycles via a Cascade IMCR/Aza Diels-Alder + CuAAC Strategy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2019.00546
Abstract: 6-Triazolylmethyl-pyrrolo[3,4-b]pyridin-5-one tris-heterocycles were synthesized in 43–57% overall yields. The two-stage synthesis involved a cascade process (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization) followed by a copper-assisted alkyne-azide [3+2] cycloaddition (CuAAC). This efficient and convergent strategy proceeded via complex terminal alkynes… read more here.
Keywords: tris heterocycles; aza diels; diels alder; chemistry ... See more keywords