Catalytic Access to 4-(sec-Alkyl)Anilines via 1,6-Conjugate Addition of Grignard Reagents to in Situ Generated aza-p-Quinone Methides
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DOI: 10.1021/acs.orglett.2c02786
Abstract: The synthesis of aniline derivatives, common building blocks in many pharmaceuticals, agrochemicals, dyes or polymers, has been limited to reactions based on benzene-toluene-xylene derivatives (BTX) due to their ample availability. Despite the large number of… read more here.
Keywords: addition grignard; grignard reagents; alkyl anilines; aza quinone ... See more keywords
Hydroquinine-catalyzed asymmetric 1,4-hydrophosphination of in situ generated aza-o-quinone methides with H-phosphine oxides
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DOI: 10.1039/d1qo00823d
Abstract: An organocatalytic enantioselective 1,4-addition of H-phosphine oxides to in situ generated aza-o-quinone methides has been successfully established using hydroquinine. read more here.
Keywords: quinone methides; aza quinone; situ generated; phosphine oxides ... See more keywords