Synthesis and Characterization of Biologically Significant 5-[N,N-dialkylamino alkoxy] azaindole 2-one, 3-thiosemicarbazones and 5-[N,N-dialkylamino alkoxy] azaindole 3-hydrazone, 2-ones.
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DOI: 10.1007/978-3-030-32633-3_27
Abstract: In the present work, new indole derivatives, i.e., 5-[N,N-di alkyl amino alkoxy] azaindole 2,3- di-one derivatives, are synthesized and characterized. These compounds were subjected to acute toxicity and then screened for antiepileptic activity on maximal… read more here.
Keywords: azaindole one; dimethyl amino; amino ethoxy; alkoxy azaindole ... See more keywords
The importance of indole and azaindole scaffold in the development of antitumor agents.
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DOI: 10.1016/j.ejmech.2020.112506
Abstract: With some indoles and azaindoles being successfully developed as anticancer drugs, the design and synthesis of indole and azaindole derivatives with remarkable antitumor activity has received increasing attention and significant progress has been made. This… read more here.
Keywords: scaffold development; azaindole; azaindole scaffold; importance indole ... See more keywords
Fluorescent 7-Azaindole N-linked 1,2,3-triazole: Synthesis and Study of Antimicrobial, Molecular Docking, ADME and DFT Properties
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DOI: 10.1039/d3nj00223c
Abstract: Two libraries of biologically essential and fluorescent 7-azaindole N-linked benzyl 1,2,3-triazole (4a-4i) and 7-azaindole N-linked phenyl 1,2,3-triazole (4j-4q) hybrids have been designed and synthesized from N-propargyl 7-azaindole, i.e., 1-prop-2-ynyl-1H-pyrrolo[2,3-b]pyridine (2)... read more here.
Keywords: azaindole linked; linked triazole; triazole synthesis; synthesis study ... See more keywords