Synthesis of 7-Azaindole Based Carbohydrazides and 1,3,4-Oxadiazoles; Antioxidant Activity, α-Glucosidase Inhibition Properties and Docking Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131343
Abstract: ABSTRACT In this current work, 7-azaindole based 1,3,4-oxadiazoles have been successfully prepared by treatment of 3-(hydrazonomethyl)-7-azaindole with the different acyl chlorides or acetic anhydrides to give the corresponding carbohydrazides, followed by iodine mediated synthetic protocol… read more here.
Keywords: antioxidant activity; activity glucosidase; glucosidase inhibition; azaindole based ... See more keywords
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c00444
Abstract: The azaindole (AI) framework continues to play a significant role in the design of new antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of AI analogs notably influences the intrinsic physicochemical… read more here.
Keywords: based frameworks; azaindole based; potential antiviral; antiviral agents ... See more keywords