A New Lead Identification Strategy: Screening an sp3‐rich and Lead‐like Compound Library Composed of 7‐Azanorbornane Derivatives
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DOI: 10.1002/cmdc.201900398
Abstract: Although the advantages of sp3‐rich, sterically complicated molecules in drug development have been pointed out, modern screening libraries are filled with planar, sp2‐rich components. Compounds that are sp3‐rich are difficult to synthesize, and thus we… read more here.
Keywords: sp3; lead identification; lead like; sp3 rich ... See more keywords