Azathioprine-Associated Complete NK Cell Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0414-6
Abstract: To the editor, We report the case of a 5-year-old Caucasian girl with very early-onset inflammatory bowel disease (VOIBD) who had inadequate response to initial therapy with azathioprine. Immune system evaluation revealed an isolated complete… read more here.
Keywords: azathioprine associated; azathioprine; disease; cell deficiency ... See more keywords
Azathioprine : un traitement prometteur des mucinoses
Sign Up to like & getrecommendations! Published in 2019 at "Annales De Dermatologie Et De Venereologie"
DOI: 10.1016/j.annder.2019.09.531
Abstract: Introduction Les mucinoses cutanees primitives regroupent un ensemble d’affections rares de pathogenie mal elucidee. Les modalites therapeutiques sont peu nombreuses et d’efficacite limitee. Nous rapportons deux observations de mucinose cutanee primitive traitee par azathioprine avec… read more here.
Keywords: par; traitement prometteur; azathioprine; traitement ... See more keywords
Photoresponsive molecularly imprinted dendrimer-based magnetic nanoparticles for photo-regulated selective separation of azathioprine
Sign Up to like & getrecommendations! Published in 2019 at "Reactive and Functional Polymers"
DOI: 10.1016/j.reactfunctpolym.2018.12.022
Abstract: Abstract This research describes the development of a poly (amidoamine) (PAMAM) dendrimer-based photoresponsive molecularly imprinted polymers (P-MIPs) for selective separation and determination of azathioprine. This study is the first involving a PAMAM dendrimer-coated magnetic nanoparticles… read more here.
Keywords: magnetic nanoparticles; molecularly imprinted; dendrimer based; azathioprine ... See more keywords
Sa1679 - Nudt15 Variant can Predict the Development of Azathioprine Induced Leucopenia and Allow Optimal Dosing in Indian Patients with Inflammatory Bowel Disease (IBD)
Sign Up to like & getrecommendations! Published in 2018 at "Gastroenterology"
DOI: 10.1016/s0016-5085(18)31503-8
Abstract: Background Azathioprine (AZA) is a widely used cost-effective option for maintenance of steroid-free remission of IBD. Leucopenia is a common complication. Recent GWAS studies have identified a strong association between NUDT 15 C415T variant and thiopurine-induced… read more here.
Keywords: azathioprine; predict development; group; ibd ... See more keywords
Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial
Sign Up to like & getrecommendations! Published in 2020 at "The Lancet Neurology"
DOI: 10.1016/s1474-4422(20)30070-3
Abstract: BACKGROUND Azathioprine is used as a first-line treatment to prevent relapses of neuromyelitis optica spectrum disorder (NMOSD). Tocilizumab has been reported to reduce NMOSD disease activity in retrospective case reports. We aimed to compare the… read more here.
Keywords: tocilizumab group; treatment; azathioprine group; azathioprine ... See more keywords
Adalimumab versus azathioprine to halt the progression of bowel damage in Crohn’s disease: application of Lémann Index
Sign Up to like & getrecommendations! Published in 2019 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2019.1686057
Abstract: Abstract Background: The Lémann Index (LI) was recently developed to evaluate the cumulative bowel damage in patients with Crohn’s disease (CD). Aims: To search for a difference between adalimumab and azathioprine to halt the progression… read more here.
Keywords: bowel; bowel damage; progression bowel; azathioprine ... See more keywords
Disseminated Tubercular Granulomas Associated with the Use of Azathioprine.
Sign Up to like & getrecommendations! Published in 2020 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2019.1704021
Abstract: Purpose: To describe a case of multiple disseminated choroidal tuberculomas in a patient of early-phase Vogt-Koyanagi- Harada (VKH) disease being treated with Azathioprine.Methods: A retrospective chart review.Results: A 55-year-old female, a diagnosed case of VKH… read more here.
Keywords: granulomas associated; granulomas; use; azathioprine ... See more keywords
NUDT15 R139C variation increases the risk of azathioprine-induced toxicity in Chinese subjects
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000010301
Abstract: Introduction: Azathioprine (AZA) is widely used as an immunosuppressive agent, and its efficacy has been recommended by many clinical studies. However, leukopenia, the most common toxicity, still restricts its clinical applications. Recent studies found that… read more here.
Keywords: azathioprine; nudt15 r139c; toxicity; induced toxicity ... See more keywords
Azathioprine-induced vanishing bile duct syndrome: the value of early thiopurine metabolism assessment.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15797
Abstract: About 15 to 28% of treated patients with thiopurines experienced adverse drug reactions, such as hematological and hepatic toxicities. A part of them is related to the polymorphic activity of the thiopurine S-methyltransferase (TPMT), the… read more here.
Keywords: duct; metabolism; azathioprine; blood ... See more keywords
Is weekly azathioprine pulse effective and safe in dermatological conditions?
Sign Up to like & getrecommendations! Published in 2020 at "Dermatologic Therapy"
DOI: 10.1111/dth.14513
Abstract: Azathioprine, a purine synthesis inhibitor is widely used as an effective immunosuppressant in several immune mediated diseases, usually in a dose of 2 to 2.5 mg/kg per day. The pulse dose of azathioprine is an… read more here.
Keywords: dermatology; azathioprine; weekly azathioprine; pulse ... See more keywords
Pretreatment HLADQA1-HLADRB1 Testing for the Prevention of Azathioprine-Induced Pancreatitis in Inflammatory Bowel Disease: A Prospective Cohort Study
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Gastroenterology"
DOI: 10.14309/ctg.0000000000000332
Abstract: INTRODUCTION: Azathioprine-induced pancreatitis is an idiosyncratic and unpredictable response, occurring in up to 7% of azathioprine-exposed patients with inflammatory bowel disease (IBD). The haplotype HLADQA1-HLADRB1*07:01A>C is strongly associated with azathioprine-induced pancreatitis in IBD. We aimed… read more here.
Keywords: induced pancreatitis; hladrb1 01a; hladqa1 hladrb1; azathioprine ... See more keywords