AZD1402/PRS-060, an inhaled AnticalinĀ® IL-4Ra antagonist, potently inhibits IL-4 induced functional effects in human whole blood, which can be employed translationally in clinical studies
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DOI: 10.1183/13993003.congress-2018.pa5248
Abstract: Introduction: AZD1402 is an Anticalin protein in clinical development that has the potential to offer an inhaled treatment for asthma patients suffering from T2-driven disease through selective blockade of IL-4RĪ±. Aims and objective: To characterise… read more here.
Keywords: potently inhibits; human whole; anticalin; whole blood ... See more keywords