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AZD4625 is a Potent and Selective Inhibitor of KRASG12C

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Published in 2022 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.mct-22-0241

Abstract: Abstract AZD4625 is a potent, selective, and orally bioavailable inhibitor of oncogenic KRASG12C as demonstrated in cellular assays and in vivo in preclinical cell line–derived and patient-derived xenograft models. In vitro and cellular assays have… read more here.

Keywords: inhibitor krasg12c; krasg12c; selective inhibitor; azd4625 potent ... See more keywords