Articles with "azd8233 antisense" as a keyword



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AZD8233 antisense oligonucleotide targeting PCSK9 does not prolong QT interval

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Published in 2022 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.15425

Abstract: AZD8233 is a proprotein convertase subtilisin/kexin type 9 (PCSK9) antisense oligonucleotide under development for treatment of hypercholesterolaemia. A prespecified concentration‐QT analysis was performed based on data from a single ascending dose study that was prospectively… read more here.

Keywords: antisense oligonucleotide; targeting pcsk9; azd8233 antisense; azd8233 ... See more keywords