Articles with "azelastine hydrochloride" as a keyword



Powder X-ray diffraction of azelastine hydrochloride, C22H25ClN3O·Cl

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Published in 2021 at "Powder Diffraction"

DOI: 10.1017/s0885715620000664

Abstract: Commercial azelastine hydrochloride crystallizes in the monoclinic space group P21/n (#14) with a = 13.7844(5), b = 16.39920(14), c = 9.41231(22) Å, β = 97.5340(20)°, V = 2109.32(4) Å3, and Z = 4. The lattice… read more here.

Keywords: azelastine hydrochloride; powder; powder ray; diffraction ... See more keywords

Validated HPLC method for simultaneous determination of azelastine hydrochloride fluticasone propionate and oxymetazoline in nasal mucosa and nasopharyngeal swabs from real human samples

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-024-82387-7

Abstract: A combination of three co-administrated drugs, such as azelastine hydrochloride (AZT), fluticasone propionate (FP), and oxymetazoline (OXY), is more effective than single therapy for the treatment of seasonal allergy and COVID-19. We established an efficient… read more here.

Keywords: method; nasal mucosa; nasopharyngeal swabs; azelastine hydrochloride ... See more keywords

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development.

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Published in 2023 at "Journal of medical microbiology"

DOI: 10.1099/jmm.0.001691

Abstract: Introduction. Azelastine hydrochloride, a second-generation histamine H1 receptor (H1R) antagonist, exhibits anti-chlamydial effects against Chlamydia trachomatis (CT) in HeLa cells (genital infection model).Hypothesis/Gap Statement. Non-antibiotic pharmaceutical interactions with CT are an understudied field and the… read more here.

Keywords: azelastine hydrochloride; infection; anti chlamydial; effects azelastine ... See more keywords
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Treatment with azelastine hydrochloride and fluticasone propionate in a single delivery device of young children and adolescents with allergic rhinitis.

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Published in 2020 at "Allergy and asthma proceedings"

DOI: 10.2500/aap.2020.41.200034

Abstract: Background: Allergic rhinitis (AR) is the most common chronic noncommunicable disease worldwide that affects any age during the human life span but raises particular concerns among the parents and caregivers of the children who are… read more here.

Keywords: allergic rhinitis; fluticasone; delivery; hydrochloride fluticasone ... See more keywords

The Multidirectional Effect of Azelastine Hydrochloride on Cervical Cancer Cells

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23115890

Abstract: A major cause of cancer cell resistance to chemotherapeutics is the blocking of apoptosis and induction of autophagy in the context of cell adaptation and survival. Therefore, new compounds are being sought, also among drugs… read more here.

Keywords: cell; azelastine hydrochloride; microscopy; cancer ... See more keywords

Development and Validation of HPTLC Method along with Forced Degradation Study for the Simultaneous Estimation of Azelastine Hydrochloride and Fluticasone Propionate in Nasal Spray Formulation using Design of Experiment Approach

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Published in 2019 at "Indian Journal of Pharmaceutical Education and Research"

DOI: 10.5530/ijper.54.1.19

Abstract: Objectives: The present research study focuses on the development of the highperformance thin layer chromatographic method using design of experiment approach for the simultaneous estimation of Azelastine hydrochloride and Fluticasone propionate along with forced degradation… read more here.

Keywords: fluticasone propionate; azelastine hydrochloride; degradation;