A prospective multicentre phase III validation study of AZGP1 as a biomarker in localized prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx247
Abstract: Background Prostate cancers (PCs) with similar characteristics at the time of diagnosis can have very different disease outcomes. Conventional biomarkers of PC still lack precision in identifying individuals at high risk of PC recurrence. While… read more here.
Keywords: phase; validation; azgp1; biomarker ... See more keywords
Abstract P6-04-16: Glucocorticoid receptor signaling elicits anti-cancer effects in endocrine resistant breast cancer via induction of AZGP1
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs19-p6-04-16
Abstract: Despite the availability of effective drugs that target ERα-positive breast cancer, ERα-positive disease still accounts for more breast cancer related deaths than any other subtype. Relapse in these patients is largely due to the development… read more here.
Keywords: azgp1; endocrine resistant; cancer; resistant breast ... See more keywords
AZGP1 Up-Regulation is a Potential Target for Andrographolide Reversing Radioresistance of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s360147
Abstract: Background Radiation resistance is a challenge that limits the therapeutic benefit of colorectal cancer (CRC) treatment, but the mechanism underlying CRC radiation resistance remains unclear. Andrographolide shows a broad-spectrum anti-tumor effect in various malignancies, including… read more here.
Keywords: azgp1; crc; colorectal cancer; resistance ... See more keywords
Changes in AZGP1 Serum Levels and Correlation With Pulse Wave Velocity After Kidney Transplantation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.692213
Abstract: Background: Zinc-alpha 2-glycoprotein (AZGP1), a secreted protein with ubiquitous tissue expression, has been controversially linked to the risk of cardiovascular disease. In a cohort of kidney transplant recipients, we measured serum AZGP1 levels after transplantation… read more here.
Keywords: azgp1; pulse wave; transplantation; wave velocity ... See more keywords
The Therapeutic Potential of Zinc-Alpha2-Glycoprotein (AZGP1) in Fibrotic Kidney Disease
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DOI: 10.3390/ijms23020646
Abstract: Chronic kidney disease (CKD) is characterized by a long-term loss of kidney function and, in most cases, by progressive fibrosis. Zinc-alpha2-glycoprotein (AZGP1) is a secreted protein, which is expressed in many different tissues and has… read more here.
Keywords: fibrotic kidney; azgp1; kidney disease; zinc alpha2 ... See more keywords
AZGP1 suppresses the process of colorectal cancer after upregulating FASN expression via mTOR signal pathway.
Sign Up to like & getrecommendations! Published in 2020 at "General physiology and biophysics"
DOI: 10.4149/gpb_2019061
Abstract: Colorectal cancer (CRC) is the most common malignant gastrointestinal tumor. Obesity has been confirmed to be closely related to the occurrence of CRC, but the specific mechanism is not clear. This study mainly explored the… read more here.
Keywords: fasn expression; azgp1; pathway; expression ... See more keywords