“Metal –free” synthesis of 1,2,3-triazoles via tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of ethyl acrylate derivatives
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DOI: 10.1016/j.tetlet.2018.05.020
Abstract: Abstract An efficient “one-pot” method for the synthesis of substituted 1,2,3-triazole derivatives in excellent yields as single regioisomer is reported. The key transformation involves an atom-efficient tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of acrylate derivatives… read more here.
Keywords: azidation intramolecular; tandem azidation; cycloaddition aromatization; acrylate derivatives ... See more keywords