Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9216-4_11
Abstract: Click chemistry has become a widely used method to insert modifications into DNA. Due to its commercial availability, 5'-ethynyl-deoxyuridine (EdU) is commonly incorporated into the DNA for subsequent modification by click reaction. However, it is… read more here.
Keywords: phase; solid phase; catalyzed alkyne; azide cycloaddition ... See more keywords
Functionalization of luminescent lanthanide-gallium metallacrowns using copper-catalyzed alkyne-azide cycloaddition and thiol-maleimide Michael addition.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2018.12.011
Abstract: The synthesis and characterization of {Ln[12-MCGaIIIN(eshi)-4]}2(iph)4 and {Ln[12-MCGaIIIN(shi)-4]}2(miph)4 metallacrowns (MCs), where shi3- is salicylhydroximate, eshi3- is 4-ethynylsalicylhydroximate, iph2- is isopthalate, and miph2- is 5-maleimidoisophthalate, is reported. The ethynyl functionality allows for coupling of MCs to… read more here.
Keywords: using copper; catalyzed alkyne; azide cycloaddition; alkyne azide ... See more keywords
Alkyne-azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors via the PI3K/Akt/NF-kB pathway.
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DOI: 10.1039/c7md00267j
Abstract: Herein, we report the isolation and synthetic modification of dehydrozingerone (DHZ, 1), a secondary metabolite present in the rhizome of Zingiber officinale. We synthesized O-propargylated dehydrozingerone, which was subsequently coupled by alkyne-azide cycloaddition (3-20) using… read more here.
Keywords: cancer; azide cycloaddition; alkyne azide; prostate cancer ... See more keywords