Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation
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DOI: 10.1021/acscentsci.1c01277
Abstract: Globo H (GH) is a tumor-associated carbohydrate antigen (TACA), and GH conjugations have been evaluated as potential cancer vaccines. However, like all carbohydrate-based vaccines, low immunogenicity is a major issue. Modifications of the TACA increase… read more here.
Keywords: immunogenicity; synthesis azido; evaluation; azido analogs ... See more keywords