Association of Azithromycin Use With Cardiovascular Mortality.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2020.8199
Abstract: Importance Azithromycin is one of the most commonly prescribed antibiotics in the US. It has been associated with an increased risk of cardiovascular death in some observational studies. Objective To estimate the relative and absolute… read more here.
Keywords: noncardiovascular death; death; risk; mortality ... See more keywords
Clinical Pharmacology Perspectives on the Antiviral Activity of Azithromycin and Use in COVID‐19
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1857
Abstract: Azithromycin (AZ) is a broad‐spectrum macrolide antibiotic with a long half‐life and a large volume of distribution. It is primarily used for the treatment of respiratory, enteric, and genitourinary bacterial infections. AZ is not approved… read more here.
Keywords: use; covid clinical; treatment; azithromycin ... See more keywords
Possible role of ABCB1 in lysosomal accumulation of azithromycin in COVID‐19 therapy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2020
Abstract: Abstract The antiviral use of azithromycin in COVID‐19 was recently reported by Damle et al. Its combination with hydroxychloroquine did not aim at preventing bacterial super‐infection as often believed, but at benefiting from their common… read more here.
Keywords: azithromycin; possible role; role abcb1; azithromycin covid ... See more keywords
The Effect of Azithromycin on Relapse in Patients with Moderate-Severe Chronic Graft Versus Host Disease (CGVHD)
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.097
Abstract: BACKGROUND A recent U.S. Food and Drug Administration (FDA) safety communication (Aug 2018) warned prescribers of the risk of relapse in patients receiving azithromycin as prophylaxis for bronchiolitis obliterans syndrome (BOS) following hematopoietic cell transplant… read more here.
Keywords: moderate severe; relapse patients; relapse; cohort ... See more keywords
Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease.
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2018.03.035
Abstract: RATIONALE According to clinical trials, azithromycin taken daily for 1 year, decreased exacerbations of chronic obstructive pulmonary disease (COPD). OBJECTIVES Effectiveness evaluation of long-term azithromycin to reduce exacerbations in severe COPD patient on optimal therapy… read more here.
Keywords: term azithromycin; long term; year; group ... See more keywords
Formulation and Evaluation of Azithromycin-Loaded Niosomal Gel: Optimization, In Vitro Studies, Rheological Characterization, and Cytotoxicity Study
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03762
Abstract: Several novel, innovative approaches for improving transdermal delivery of BCS class III drugs have been proposed. Despite their great aqueous solubility, BCS class III drugs have the drawback of limited permeability. The objective of the… read more here.
Keywords: niosomal gel; gel; bcs class; drug ... See more keywords
Repurposing azithromycin for neuroprotection in neonates
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Research"
DOI: 10.1038/s41390-019-0443-3
Abstract: In this issue of Pediatric Research, Barks and his colleagues from the University of Michigan tested the effectiveness of intraperitoneal (i.p.) azithromycin as an anti-inflammatory post-injury (rescue) neuroprotectant in the P7 (near-term equivalent) and P10… read more here.
Keywords: treatment; azithromycin; model; brain ... See more keywords
Weekly azithromycin for 48 weeks impacts nasopharyngeal microbial prevalence and Streptococcus pneumoniae serotypes in children with HIV-associated chronic lung disease
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-23693-6
Abstract: HIV-associated chronic lung disease (HCLD) accounts for over 50% of deaths in children living with HIV. Azithromycin reduces the risk of respiratory exacerbations in children with HCLD, but its impact on respiratory pathogens and Streptococcus… read more here.
Keywords: pneumoniae serotypes; chronic lung; hiv associated; azithromycin ... See more keywords
Dry powder formulation of azithromycin for COVID-19 therapeutics
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2023.2175924
Abstract: Abstract Azithromycin is an antibiotic proposed as a treatment for the coronavirus disease 2019 (COVID-19) due to its immunomodulatory activity. The aim of this study is to develop dry powder formulations of azithromycin-loaded poly(lactic-co-glycolic acid)… read more here.
Keywords: dry powder; powder formulation; covid; powder ... See more keywords
The safety profile of Azithromycin in pediatrics: a pharmacovigilance disproportionality analysis.
Sign Up to like & getrecommendations! Published in 2024 at "Expert opinion on drug safety"
DOI: 10.1080/14740338.2024.2443797
Abstract: AIM To mine and analyze adverse drug events (ADEs) signals of azithromycin use in children in the real world to inform the safety assessment of azithromycin use in children. METHODS ADE reports from the FDA… read more here.
Keywords: profile azithromycin; use children; safety profile; azithromycin ... See more keywords
UV activation of hydrogen peroxide for removal of azithromycin antibiotic from aqueous solution: determination of optimum conditions by response surface methodology
Sign Up to like & getrecommendations! Published in 2019 at "Toxin Reviews"
DOI: 10.1080/15569543.2018.1517803
Abstract: Abstract Antibiotics have caused major concerns in environmental control due to the cumulative adverse effects on human health. This study investigates the effect of four variables: pH (3, 6, and 9), azithromycin concentration (2, 6,… read more here.
Keywords: methodology; hydrogen peroxide; removal; azithromycin ... See more keywords