Articles with "azithromycin" as a keyword



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Association of Azithromycin Use With Cardiovascular Mortality.

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Published in 2020 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2020.8199

Abstract: Importance Azithromycin is one of the most commonly prescribed antibiotics in the US. It has been associated with an increased risk of cardiovascular death in some observational studies. Objective To estimate the relative and absolute… read more here.

Keywords: noncardiovascular death; death; risk; mortality ... See more keywords
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Clinical Pharmacology Perspectives on the Antiviral Activity of Azithromycin and Use in COVID‐19

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Published in 2020 at "Clinical Pharmacology and Therapeutics"

DOI: 10.1002/cpt.1857

Abstract: Azithromycin (AZ) is a broad‐spectrum macrolide antibiotic with a long half‐life and a large volume of distribution. It is primarily used for the treatment of respiratory, enteric, and genitourinary bacterial infections. AZ is not approved… read more here.

Keywords: use; covid clinical; treatment; azithromycin ... See more keywords
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Possible role of ABCB1 in lysosomal accumulation of azithromycin in COVID‐19 therapy

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Published in 2020 at "Clinical Pharmacology and Therapeutics"

DOI: 10.1002/cpt.2020

Abstract: Abstract The antiviral use of azithromycin in COVID‐19 was recently reported by Damle et al. Its combination with hydroxychloroquine did not aim at preventing bacterial super‐infection as often believed, but at benefiting from their common… read more here.

Keywords: azithromycin; possible role; role abcb1; azithromycin covid ... See more keywords
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The Effect of Azithromycin on Relapse in Patients with Moderate-Severe Chronic Graft Versus Host Disease (CGVHD)

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Published in 2019 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2018.12.097

Abstract: BACKGROUND A recent U.S. Food and Drug Administration (FDA) safety communication (Aug 2018) warned prescribers of the risk of relapse in patients receiving azithromycin as prophylaxis for bronchiolitis obliterans syndrome (BOS) following hematopoietic cell transplant… read more here.

Keywords: moderate severe; relapse patients; relapse; cohort ... See more keywords
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Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease.

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Published in 2018 at "Respiratory medicine"

DOI: 10.1016/j.rmed.2018.03.035

Abstract: RATIONALE According to clinical trials, azithromycin taken daily for 1 year, decreased exacerbations of chronic obstructive pulmonary disease (COPD). OBJECTIVES Effectiveness evaluation of long-term azithromycin to reduce exacerbations in severe COPD patient on optimal therapy… read more here.

Keywords: term azithromycin; long term; year; group ... See more keywords
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Formulation and Evaluation of Azithromycin-Loaded Niosomal Gel: Optimization, In Vitro Studies, Rheological Characterization, and Cytotoxicity Study

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c03762

Abstract: Several novel, innovative approaches for improving transdermal delivery of BCS class III drugs have been proposed. Despite their great aqueous solubility, BCS class III drugs have the drawback of limited permeability. The objective of the… read more here.

Keywords: niosomal gel; gel; bcs class; drug ... See more keywords
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Repurposing azithromycin for neuroprotection in neonates

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Published in 2019 at "Pediatric Research"

DOI: 10.1038/s41390-019-0443-3

Abstract: In this issue of Pediatric Research, Barks and his colleagues from the University of Michigan tested the effectiveness of intraperitoneal (i.p.) azithromycin as an anti-inflammatory post-injury (rescue) neuroprotectant in the P7 (near-term equivalent) and P10… read more here.

Keywords: treatment; azithromycin; model; brain ... See more keywords
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Dry powder formulation of azithromycin for COVID-19 therapeutics

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Published in 2023 at "Journal of Microencapsulation"

DOI: 10.1080/02652048.2023.2175924

Abstract: Abstract Azithromycin is an antibiotic proposed as a treatment for the coronavirus disease 2019 (COVID-19) due to its immunomodulatory activity. The aim of this study is to develop dry powder formulations of azithromycin-loaded poly(lactic-co-glycolic acid)… read more here.

Keywords: dry powder; powder formulation; covid; powder ... See more keywords
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UV activation of hydrogen peroxide for removal of azithromycin antibiotic from aqueous solution: determination of optimum conditions by response surface methodology

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Published in 2019 at "Toxin Reviews"

DOI: 10.1080/15569543.2018.1517803

Abstract: Abstract Antibiotics have caused major concerns in environmental control due to the cumulative adverse effects on human health. This study investigates the effect of four variables: pH (3, 6, and 9), azithromycin concentration (2, 6,… read more here.

Keywords: methodology; hydrogen peroxide; removal; azithromycin ... See more keywords
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Effect of azithromycin on bronchiolitis obliterans syndrome in posttransplant recipients: A systematic review and meta-analysis

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000029160

Abstract: Background: Bronchiolitis obliterans syndrome (BOS) is a devastating complication that occurs after transplantation. Although azithromycin is currently used for the treatment of BOS, the evidence is sparse and controversial. The aim of this meta-analysis is… read more here.

Keywords: meta analysis; effect; obliterans syndrome; term ... See more keywords
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Azithromycin and Major Adverse Kidney Events in Critically Ill Patients With Sepsis-Associated Acute Kidney Injury

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Published in 2021 at "SHOCK"

DOI: 10.1097/shk.0000000000001883

Abstract: ABSTRACT Background: Sepsis-associated acute kidney injury (SA-AKI) is associated with significant morbidity and mortality. Immune dysregulation is a hallmark of sepsis, with important contributions to organ dysfunction including injury and repair mechanisms in AKI. Macrolide… read more here.

Keywords: sepsis; critically ill; injury; azithromycin ... See more keywords