Azithromycin resistance levels and mechanisms in Escherichia coli
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DOI: 10.1038/s41598-019-42423-3
Abstract: Despite azithromycin being used in some countries to treat infections caused by Gram-negative pathogens, no resistance breakpoint for Escherichia coli exists. The aim of this study was to analyse the levels and mechanisms of azithromycin… read more here.
Keywords: resistance levels; mechanisms escherichia; escherichia coli; azithromycin resistance ... See more keywords
Neisseria gonorrhoeae 23S rRNA A2059G mutation is the only determinant necessary for high-level azithromycin resistance and improves in vivo biological fitness
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DOI: 10.1093/jac/dky438
Abstract: Objectives The global emergence of Neisseria gonorrhoeae isolates displaying high-level azithromycin resistance is a major concern for the currently recommended azithromycin/ceftriaxone dual therapy. N. gonorrhoeae high-level azithromycin resistance has been associated with an A2059G mutation… read more here.
Keywords: a2059g mutation; level azithromycin; high level; azithromycin resistance ... See more keywords
Tracking the Emergence of Azithromycin Resistance in Multiple Genotypes of Typhoidal Salmonella
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DOI: 10.1128/mbio.03481-20
Abstract: In the early 1900s, with mortality of ∼30%, typhoid and paratyphoid (caused by Salmonella Typhi and Paratyphi A) ravaged parts of the world; with improved water, sanitation, and hygiene in resource-rich countries and the advent… read more here.
Keywords: mutation; acrb r717q; typhi; resistance ... See more keywords
Genetic Characterization of a Conjugative Plasmid That Encodes Azithromycin Resistance in Enterobacteriaceae
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DOI: 10.1128/spectrum.00788-22
Abstract: In this study, we identified a conjugative plasmid carrying a novel azithromycin resistance gene, erm(42), from a clinical K. pneumoniae strain. Conjugation of this plasmid into Salmonella conjugants conferred resistance to azithromycin, which is considered… read more here.
Keywords: conjugative plasmid; plasmid; azithromycin resistance; salmonella ... See more keywords
Antimicrobial Resistance and Mechanisms of Azithromycin Resistance in Nontyphoidal Salmonella Isolates in Taiwan, 2017 to 2018
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DOI: 10.1128/spectrum.03364-22
Abstract: Antimicrobial resistance in NTS isolates is a major public health concern in Taiwan, and the mechanisms of azithromycin resistance are rarely investigated. Azithromycin and carbapenems are the last resort for the treatment of invasive salmonellosis… read more here.
Keywords: azithromycin resistance; nts isolates; salmonella; resistance ... See more keywords
P617 Molecular typing of mycoplasma genitalium shows a diverse epidemic with limited azithromycin resistance in south africa
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DOI: 10.1136/sextrans-2019-sti.685
Abstract: Background The occurrence of azithromycin resistance in M. genitalium infection is unknown in Africa, where diagnostic resources are limited and STIs are managed syndromically. This study aims to gain insight in the molecular epidemiology including… read more here.
Keywords: south africa; azithromycin resistance; resistance; molecular typing ... See more keywords
A new plasmid carrying mphA causes prevalence of azithromycin resistance in enterotoxigenic Escherichia coli serogroup O6
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DOI: 10.1186/s12866-020-01927-z
Abstract: At present, azithromycin has become an effective treatment for severe diarrhea caused by Enterotoxigenic Escherichia coli (ETEC) infection. However, enterobacteria have begun to develop resistance to azithromycin and have attracted attention in recent years. This… read more here.
Keywords: escherichia coli; azithromycin resistance; resistance; etec serogroup ... See more keywords