Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells.
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DOI: 10.1021/acschembio.7b00339
Abstract: Azoles are the most commonly used class of antifungal drugs, yet where they localize within fungal cells and how they are imported remain poorly understood. Azole antifungals target lanosterol 14α-demethylase, a cytochrome P450, encoded by… read more here.
Keywords: cytochrome p450; antifungal drugs; azole class; class antifungal ... See more keywords