Azole derivatives inhibit wildtype butyrylcholinesterase and its common mutants.
Sign Up to like & getrecommendations! Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22071
Abstract: Azoles, which have been used for antifungal chemotherapy for decades, have recently been of interest for their efficacy against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). There is little known about the potential of azoles against BChE,… read more here.
Keywords: azole derivatives; derivatives inhibit; bche; inhibit wildtype ... See more keywords
One pot solvent-free solid state synthesis, photophysical properties and crystal structure of substituted azole derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.12.095
Abstract: Abstract A solvent-free solid state method has been developed to synthesize three series of substituted azole derivatives (including 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole) in high yields by condensation cyclization of N,N′-bishydrazide derivatives with corresponding cyclization agents,… read more here.
Keywords: free solid; solvent free; photophysical properties; structure ... See more keywords