Seminal plasma miRNAs in Klinefelter syndrome and in obstructive and non-obstructive azoospermia
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05552-x
Abstract: MicroRNAs are small, non-coding, single-strand oligonucleotides which regulate gene expression. There is little evidence in the literature about their role in azoospermia and no studies have investigated their presence in the seminal plasma of men… read more here.
Keywords: klinefelter syndrome; non obstructive; azoospermia; seminal plasma ... See more keywords
Azoospermia: Is it worth waiting for the confirmation of the semen abnormality to start an infertility assessment?
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14487
Abstract: Azoospermia is found in about 1% of men in the general population and in about 10%–15% of infertile men. Upon discovery of semen analysis abnormality, another test must be performed after an interval of 3 months… read more here.
Keywords: infertility assessment; semen analysis; azoospermia; infertility ... See more keywords
It is time for a more standardized approach to identifying surgical outcome of non‐obstructive azoospermia
Sign Up to like & getrecommendations! Published in 2017 at "Andrology"
DOI: 10.1111/andr.12325
Abstract: Non-obstructive azoospermia (NOA) is one of the most disastrous and frustrating disease conditions for the young infertile couples and doctors dealing with it. Except for special cases such as hypogonadotropic hypogonadism, most medical therapies for… read more here.
Keywords: micro tese; outcome; azoospermia; retrieval rate ... See more keywords
Experimental validation of seminal miR‐31‐5p as biomarker for azoospermia and evaluation of the effect of preanalytical variables
Sign Up to like & getrecommendations! Published in 2022 at "Andrology"
DOI: 10.1111/andr.13286
Abstract: Predicting the origin of azoospermia with non‐invasive biomarkers is clinically relevant for determining the chance of successful sperm retrieval from the testes before attempting assisted reproduction treatment. Here, the semen small extracellular vesicle microRNA miR‐31‐5p‐based… read more here.
Keywords: experimental validation; validation seminal; biomarker; mir ... See more keywords
Seminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermia.
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DOI: 10.1111/andr.13461
Abstract: BACKGROUND Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive (OA), or non-obstructive/secretory azoospermia (NOA/SA), as well as for inferring the spermatogenic reserve of the testis of NOA/SA patients, are of great interest… read more here.
Keywords: non invasive; expression; sncrna; sperm retrieval ... See more keywords
Interaction between Host and Microbes in the Semen of Patients with Idiopathic Nonobstructive Azoospermia
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.04365-22
Abstract: Idiopathic nonobstructive azoospermia is one of the great challenges in assisted reproductive therapy. Although microdissection testicular sperm extraction technology is currently available, many men with iNOA still face the problem of poor sperm retrieval and… read more here.
Keywords: poor sperm; nonobstructive azoospermia; sperm quality; idiopathic nonobstructive ... See more keywords
Testicular expression of TDRD1, TDRD5, TDRD9 and TDRD12 in azoospermia
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Genetics"
DOI: 10.1186/s12881-020-0970-0
Abstract: Tudor domain-containing proteins (TDRDs) play a critical role in piRNA biogenesis and germ cell development. piRNAs, small regulatory RNAs, act by silencing of transposons during germline development and it has recently been shown in animal… read more here.
Keywords: tdrd1 tdrd5; expression tdrd1; azoospermia; tdrd5 tdrd9 ... See more keywords
Association of Single Nucleotide Polymorphisms in the PYGO2 and PRDM9 Genes with Idiopathic Azoospermia in Iranian Infertile Male Patients
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2022.93009.2433
Abstract: Background: Azoospermia is a risk factor for infertility affecting approximately 1% of the male population. Genetic factors are associated with non-obstructive azoospermia (NOA). Pygo2 and PRDM9 genes are involved in the spermatogenesis process. The present… read more here.
Keywords: prdm9 genes; association single; pygo2 prdm9; pygo2 ... See more keywords
Integrative bioinformatics analysis to identify novel biomarkers associated with non-obstructive azoospermia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1088261
Abstract: Aim This study aimed to identify autophagy-related genes (ARGs) associated with non-obstructive azoospermia and explore the underlying molecular mechanisms. Methods Two datasets associated with azoospermia were downloaded from the Gene Expression Omnibus database, and ARGs… read more here.
Keywords: hub genes; associated non; non obstructive; obstructive azoospermia ... See more keywords
Chronic Immune-Mediated Orchitis Is the Major Cause of Acquired Non-obstructive Azoospermia in Dogs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.865967
Abstract: Azoospermia, the lack of spermatozoa in the ejaculate, is the most common finding in infertile but otherwise healthy male dogs and represents an increasing reproductive health issue in men, too. The diagnosis can be further… read more here.
Keywords: non obstructive; chronic immune; etiology; obstructive azoospermia ... See more keywords
Y-chromosome microdeletions in nonobstructive azoospermia and severe oligozoospermia
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DOI: 10.4103/1008-682x.172827
Abstract: The aim of the present work was to present the outcomes of the patients with Y-chromosome microdeletions treated by intracytoplasmic sperm injection (ICSI), either using fresh (TESE) or frozen-thawed (TESE-C) testicular sperm and ejaculated sperm… read more here.
Keywords: chromosome microdeletions; azfc tese; azoospermia; rate ... See more keywords