Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental hematology"
DOI: 10.1016/j.exphem.2017.09.010
Abstract: The genetic abnormalities underlying multiple myeloma (MM) are notoriously complex and intraclonal heterogeneity is a common disease feature. In the current study, we describe the establishment of a monoclonal immunoglobulin A (IgA) kappa (κ) MM… read more here.
Keywords: chain; study; cell line; b11 ... See more keywords
Biparatopic anti-PCSK9 antibody enhances the LDL-uptake in HepG2 cells
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DOI: 10.1038/s41598-024-66290-9
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising therapeutic target to reduce lipids. In 2020, we reported a chimeric camelid-human heavy chain antibody VHH-B11-Fc targeting PCSK9. Recently, it was verified that VHH-B11… read more here.
Keywords: ldl uptake; vhh b11; biparatopic anti; antibody ... See more keywords
Nuclear electric dipole moment in the cluster model with a triton: Li7 and B11
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DOI: 10.1103/physrevc.100.055501
Abstract: We calculate the electric dipole moment (EDM) of the nuclei Li7 and B11 in the cluster model with α (He4) and triton (H3) clusters as degrees of freedom. The Li7 and B11 nuclei are treated… read more here.
Keywords: li7 b11; cluster model; b11; electric dipole ... See more keywords
A Litopenaeus vannamei Hemocyanin-Derived Antimicrobial Peptide (Peptide B11) Attenuates Cancer Cells’ Proliferation
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DOI: 10.3390/molecules23123202
Abstract: Antimicrobial peptides play important roles in the immune response to pathogens and tumor cells; for this reason, they are being exploited for therapeutic use. In this study, we describe a Litopenaeus vannamei hemocyanin-derived peptide, denoted… read more here.
Keywords: hemocyanin derived; peptide b11; proliferation; b11 ... See more keywords