Triterpenoid saponins from Polaskia chichipe Backbg. and their inhibitory or promotional effects on the melanogenesis of B16 melanoma cells
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DOI: 10.1007/s11418-017-1082-9
Abstract: Five new oleanane-type saponins 1–5 together with a known saponin 6 and a steroidal glycoside 7 were isolated from Polaskia chichipe Backbg., and their structures were determined from their 1D and 2D NMR and HRFABMS… read more here.
Keywords: effects melanogenesis; chichipe backbg; b16 melanoma; polaskia chichipe ... See more keywords
Dnmt3a is required for the tumor stemness of B16 melanoma cells.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmz081
Abstract: The relationship of carcinogenesis and DNA methyltransferases has attracted extensive attention in tumor research. We reported previously that inhibition of de novo DNA methyltransferase 3a (Dnmt3a) in murine B16 melanoma cells significantly suppressed tumor growth… read more here.
Keywords: b16 melanoma; dnmt3a; differentiation; tumor ... See more keywords
Carfilzomib in Combination with Bortezomib Enhances Apoptotic Cell Death in B16-F1 Melanoma Cells
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DOI: 10.3390/biology10020153
Abstract: Simple Summary The incidence rate of metastatic melanoma has been rapidly increasing worldwide and its 5-year survival rate is very low. Due to partial responses, various side effects, and resistance to any known cancer therapeutics,… read more here.
Keywords: melanoma; combination; treatment; b16 melanoma ... See more keywords
Human Recombinant DNase I (Pulmozyme®) Inhibits Lung Metastases in Murine Metastatic B16 Melanoma Model That Correlates with Restoration of the DNase Activity and the Decrease SINE/LINE and c-Myc Fragments in Blood Cell-Free DNA
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DOI: 10.3390/ijms222112074
Abstract: Tumor-associated cell-free DNAs (cfDNA) play an important role in the promotion of metastases. Previous studies proved the high antimetastatic potential of bovine pancreatic DNase I and identified short interspersed nuclear elements (SINEs) and long interspersed… read more here.
Keywords: dnase; lung metastases; b16 melanoma; cell free ... See more keywords
Mechanophenotyping of B16 Melanoma Cell Variants for the Assessment of the Efficacy of (-)-Epigallocatechin Gallate Treatment Using a Tapered Microfluidic Device
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DOI: 10.3390/mi10030207
Abstract: Metastatic cancer cells are known to have a smaller cell stiffness than healthy cells because the small stiffness is beneficial for passing through the extracellular matrix when the cancer cells instigate a metastatic process. Here… read more here.
Keywords: b16; b16 melanoma; cancer cells; cell ... See more keywords