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Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109127
Abstract: Inhibition of mouse double minute 2 homolog (MDM2)-p53 interaction and reactivation of p53 signaling have been explored as effective anticancer therapeutic strategy. The potent and specific antitumor activity shown by Nutlins, first class of MDM2-p53…
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Keywords:
lqfm126;
activity;
antitumoral activity;
melanoma cells ... See more keywords
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Published in 2019 at "European Journal of Integrative Medicine"
DOI: 10.1016/j.eujim.2018.10.013
Abstract: Abstract Introduction The demand for treatment of hyperpigmentation disorders are on the rise. Artemisia capillaris is a traditional herbal plant widely used in skin protective remedies. In the present study, the inhibitory effect of Artemisia…
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Keywords:
active compound;
artemisia capillaris;
b16f10 melanoma;
compound ... See more keywords
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Published in 2019 at "Applied Biological Chemistry"
DOI: 10.1186/s13765-019-0468-7
Abstract: In this study, the antimelanogenic activity of piperlongumine in murine B16F10 melanoma cells and zebrafish was investigated, and its mode of antimelanogenic action was elucidated using quantitative reverse transcription-polymerase chain reaction. A melanocyte-stimulating hormone (α-MSH,…
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Keywords:
melanoma cells;
antimelanogenic activity;
b16f10 melanoma;
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Published in 2019 at "Nanomedicine"
DOI: 10.2217/nnm-2019-0022
Abstract: Aim: Garcinol (GAR)-loaded cationic nanoliposomes were developed to achieve potential antitumor efficacy on B16F10 melanoma cells in vitro and in vivo. Materials & methods: Two different phospholipids namely, distearoyl phosphatidylcholine (DSPC) and dipalmitoyl phosphatidylcholine (DPPC)…
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Keywords:
garcinol;
vitro vivo;
cationic nanoliposomes;
gar ... See more keywords
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Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11091636
Abstract: Yuzu (Citrus junos) is a citrus plant native to Asian countries, including Korea, Japan, and China. Yuzu peel and seed contain abundant vitamin C, citric acid, and polyphenols. Although the antioxidative and antimelanogenic activities of…
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Keywords:
antioxidant activity;
yuzu seed;
melanoma cells;
b16f10 melanoma ... See more keywords
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Published in 2022 at "Foods"
DOI: 10.3390/foods11030391
Abstract: Peptide Phe-Thr-Gly-Met-Leu (FTGML) is a bioactive oligopeptide with tyrosinase inhibitory activity derived from gelatin hydrolysate of grass carp scales. Previous studies have shown that FTGML addition can effectively inhibit mushroom tyrosinase activity in vitro, and…
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Keywords:
anti melanin;
melanin;
melanoma cells;
b16f10 melanoma ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094634
Abstract: Adrenergic receptors (AR) belong to the G protein-coupled receptor superfamily and regulate migration and proliferation in various cell types. The objective of this study was to evaluate whether β-AR stimulation affects the antiproliferative action of…
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Keywords:
cell;
cell proliferation;
proliferation;
b16f10 melanoma ... See more keywords
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Published in 2023 at "Life"
DOI: 10.3390/life13040934
Abstract: Melanogenesis involves a synthesis of melanin pigment and is regulated by tyrosinase. The addition of whitening agents with tyrosinase-inhibiting properties in cosmetics is becoming increasingly important. In this study, the ethanolic extracts from twelve seaweeds…
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Keywords:
challengeriae;
melanoma cells;
b16f10 melanoma;
tyrosinase ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092613
Abstract: The objectives of this study were to investigate the melanogenetic potential of the psoralen derivatives 5-hydroxypsoralen, 5-methoxypsoralen, 8-hydroxypsoralen, 8-methoxypsoralen, and 5,8-dimethoxypsoralen in B16F10 melanoma cells. The results indicated that melanin production is significantly stimulated in…
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Keywords:
psoralen derivatives;
catenin;
melanoma cells;
b16f10 melanoma ... See more keywords
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Published in 2022 at "Nutrients"
DOI: 10.3390/nu14235044
Abstract: As one of the prominent medicinal plants listed in the Chinese pharmacopoeia (2020), Saussurea involucrata (Kar. et Kir.) Sch.-Bip was demonstrated to possess various therapeutic effects. In our recent research, we extracted the polysaccharides from…
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Keywords:
anti melanogenesis;
b16f10 melanoma;
forskolin induced;
saussurea involucrata ... See more keywords