Articles with "b16f10 melanoma" as a keyword



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Antiangiogenic and antitumoral activity of LQFM126 prototype against B16F10 melanoma cells.

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Published in 2020 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2020.109127

Abstract: Inhibition of mouse double minute 2 homolog (MDM2)-p53 interaction and reactivation of p53 signaling have been explored as effective anticancer therapeutic strategy. The potent and specific antitumor activity shown by Nutlins, first class of MDM2-p53… read more here.

Keywords: lqfm126; activity; antitumoral activity; melanoma cells ... See more keywords
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Leukodin isolated from Artemisia capillaris inhibits alpha-melanocyte stimulating hormone induced melanogenesis in B16F10 melanoma cells

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Published in 2019 at "European Journal of Integrative Medicine"

DOI: 10.1016/j.eujim.2018.10.013

Abstract: Abstract Introduction The demand for treatment of hyperpigmentation disorders are on the rise. Artemisia capillaris is a traditional herbal plant widely used in skin protective remedies. In the present study, the inhibitory effect of Artemisia… read more here.

Keywords: active compound; artemisia capillaris; b16f10 melanoma; compound ... See more keywords
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Antimelanogenic activities of piperlongumine derived from Piper longum on murine B16F10 melanoma cells in vitro and zebrafish embryos in vivo: its molecular mode of depigmenting action

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Published in 2019 at "Applied Biological Chemistry"

DOI: 10.1186/s13765-019-0468-7

Abstract: In this study, the antimelanogenic activity of piperlongumine in murine B16F10 melanoma cells and zebrafish was investigated, and its mode of antimelanogenic action was elucidated using quantitative reverse transcription-polymerase chain reaction. A melanocyte-stimulating hormone (α-MSH,… read more here.

Keywords: melanoma cells; antimelanogenic activity; b16f10 melanoma;
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Garcinol-loaded novel cationic nanoliposomes: in vitro and in vivo study against B16F10 melanoma tumor model.

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Published in 2019 at "Nanomedicine"

DOI: 10.2217/nnm-2019-0022

Abstract: Aim: Garcinol (GAR)-loaded cationic nanoliposomes were developed to achieve potential antitumor efficacy on B16F10 melanoma cells in vitro and in vivo. Materials & methods: Two different phospholipids namely, distearoyl phosphatidylcholine (DSPC) and dipalmitoyl phosphatidylcholine (DPPC)… read more here.

Keywords: garcinol; vitro vivo; cationic nanoliposomes; gar ... See more keywords
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Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathway

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Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11091636

Abstract: Yuzu (Citrus junos) is a citrus plant native to Asian countries, including Korea, Japan, and China. Yuzu peel and seed contain abundant vitamin C, citric acid, and polyphenols. Although the antioxidative and antimelanogenic activities of… read more here.

Keywords: antioxidant activity; yuzu seed; melanoma cells; b16f10 melanoma ... See more keywords
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Effect of Grass Carp Scale Collagen Peptide FTGML on cAMP-PI3K/Akt and MAPK Signaling Pathways in B16F10 Melanoma Cells and Correlation between Anti-Melanin and Antioxidant Properties

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Published in 2022 at "Foods"

DOI: 10.3390/foods11030391

Abstract: Peptide Phe-Thr-Gly-Met-Leu (FTGML) is a bioactive oligopeptide with tyrosinase inhibitory activity derived from gelatin hydrolysate of grass carp scales. Previous studies have shown that FTGML addition can effectively inhibit mushroom tyrosinase activity in vitro, and… read more here.

Keywords: anti melanin; melanin; melanoma cells; b16f10 melanoma ... See more keywords
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Crosstalk between β2- and α2-Adrenergic Receptors in the Regulation of B16F10 Melanoma Cell Proliferation

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23094634

Abstract: Adrenergic receptors (AR) belong to the G protein-coupled receptor superfamily and regulate migration and proliferation in various cell types. The objective of this study was to evaluate whether β-AR stimulation affects the antiproliferative action of… read more here.

Keywords: cell; cell proliferation; proliferation; b16f10 melanoma ... See more keywords
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Inhibitory Effects of Caulerpa racemosa, Ulva intestinalis, and Lobophora challengeriae on Tyrosinase Activity and α-MSH-Induced Melanogenesis in B16F10 Melanoma Cells

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Published in 2023 at "Life"

DOI: 10.3390/life13040934

Abstract: Melanogenesis involves a synthesis of melanin pigment and is regulated by tyrosinase. The addition of whitening agents with tyrosinase-inhibiting properties in cosmetics is becoming increasingly important. In this study, the ethanolic extracts from twelve seaweeds… read more here.

Keywords: challengeriae; melanoma cells; b16f10 melanoma; tyrosinase ... See more keywords
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Mechanistic Insights into the Ameliorating Effect of Melanogenesis of Psoralen Derivatives in B16F10 Melanoma Cells

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27092613

Abstract: The objectives of this study were to investigate the melanogenetic potential of the psoralen derivatives 5-hydroxypsoralen, 5-methoxypsoralen, 8-hydroxypsoralen, 8-methoxypsoralen, and 5,8-dimethoxypsoralen in B16F10 melanoma cells. The results indicated that melanin production is significantly stimulated in… read more here.

Keywords: psoralen derivatives; catenin; melanoma cells; b16f10 melanoma ... See more keywords
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Anti-Melanogenesis Effect of Polysaccharide from Saussurea involucrata on Forskolin-Induced Melanogenesis in B16F10 Melanoma Cells

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Published in 2022 at "Nutrients"

DOI: 10.3390/nu14235044

Abstract: As one of the prominent medicinal plants listed in the Chinese pharmacopoeia (2020), Saussurea involucrata (Kar. et Kir.) Sch.-Bip was demonstrated to possess various therapeutic effects. In our recent research, we extracted the polysaccharides from… read more here.

Keywords: anti melanogenesis; b16f10 melanoma; forskolin induced; saussurea involucrata ... See more keywords