Aortic root diameter is associated with HLA-B27: identifying the patient with ankylosing spondylitis at risk for aortic valve regurgitation
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology International"
DOI: 10.1007/s00296-021-05040-w
Abstract: To assess the association between the aortic root diameter in HLA-B27 positive (+) and HLA-B27 negative (−) ankylosing spondylitis (AS) patients from the CARDAS cohort. The CARDAS study is a cross-sectional study in AS patients… read more here.
Keywords: aortic root; hla b27; b27 patients; b27 ... See more keywords
Younger age of onset and uveitis associated with HLA-B27 and delayed diagnosis in Thai patients with axial spondyloarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-93001-5
Abstract: To identify characteristics associated with HLA-B27, and to identify factors associated with delayed diagnosis in Thai patients with axial spondyloarthritis (axSpA). This cross-sectional study included Thai patients were diagnosed with axSpA by a rheumatologist at… read more here.
Keywords: b27; diagnosis; hla b27; associated hla ... See more keywords
Clinical Characteristics of HLA-B27-Associated Anterior Uveitis in a Finnish Population-Based Cohort
Sign Up to like & getrecommendations! Published in 2024 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2024.2360593
Abstract: ABSTRACT Purpose To evaluate the clinical characteristics, treatment outcomes and ocular complications in patients with HLA-B27-associated AU compared to those without HLA-B27. Methods From the population-based data of all adult patients with AU during 2009–2020… read more here.
Keywords: etiology; hla b27; b27 hla; b27 ... See more keywords
Human leucocyte antigen-B27 testing in clinical practice: a global perspective
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000946
Abstract: Purpose of review The association between human leucocyte antigen (HLA)-B27 and spondyloarthritis (SpA) was described half a century ago. New insights about pathophysiologic pathways and their role in bone formation were reported in recent years… read more here.
Keywords: b27; human leucocyte; leucocyte antigen; hla b27 ... See more keywords
AB0711 Review of management of HLA B27 positive uveitis patient attending a tertiary hospital – how good are we?
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.4511
Abstract: Background Delay in diagnosing Spondyloarthroapthy is well documented. One of the reasons for the delay is the presentation of these group of patients to different specialties due to variety of extra articular manifestations. Acute anterior… read more here.
Keywords: b27; hla b27; rheumatology; b27 positive ... See more keywords
SAT0545 ULTRASONOGRAPHIC ENTHESEAL AND JOINT INVOLVEMENT IN PATIENTS WITH ACUTE ANTERIOR UVEITIS: A MONOCENTRIC CROSS-SECTIONAL STUDY.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.6392
Abstract: Few studies have been investigating ultrasonographic (US) changes at peripheral entheses and joints in patients with anterior acute uveitis (AAU)1and none has been comparing non granulomatous uveitis (AANGU) with granulomatous uveitis (AAGU).To investigate prevalence of… read more here.
Keywords: uveitis; aangu b27; enthesis; b27 ... See more keywords
Targeted Delivery of the HLA-B∗27-Binding Peptide into the Endoplasmic Reticulum Suppresses the IL-23/IL-17 Axis of Immune Cells in Spondylarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/4016802
Abstract: Ankylosing spondylitis (AS) is highly associated with the expression of human leukocyte antigen-B27 (HLA-B∗27). HLA-B∗27 heavy chain (B27-HC) has an intrinsic propensity to fold slowly, leading to the accumulation of the misfolded B27-HC in the… read more here.
Keywords: b27; endoplasmic reticulum; delivery hla; hla ... See more keywords
Clinical Features of Acute Anterior Uveitis with Complicated Course in a Slovenian Patient Population
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ophthalmology"
DOI: 10.1155/2020/6079146
Abstract: Purpose To report on patients who needed hospitalization due to acute anterior uveitis (AAU) and within this group to compare clinical features and outcomes of treatment of HLA-B27+ and HLA-B27− AAU in the population of… read more here.
Keywords: b27; anterior uveitis; hla b27; group ... See more keywords
The gut microbiome and HLA-B27-associated anterior uveitis: a case-control study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-024-03109-4
Abstract: Background The human gut microbiome (GM) is involved in inflammation and immune response regulation. Dysbiosis, an imbalance in this ecosystem, facilitates pathogenic invasion, disrupts immune equilibrium, and potentially triggers diseases including various human leucocyte antigen… read more here.
Keywords: non infectious; anterior uveitis; b27 associated; gut microbiome ... See more keywords
The Frequency of HLA-B27 in a Colombian Population with Signs of Spondyloarthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Current rheumatology reviews"
DOI: 10.2174/1573397113666170329121552
Abstract: BACKGROUND The strong association between HLA-B27 and spondyloarthritis (SpA) has demonstrated that typing the HLA-B27 antigen is a crucial step in diagnosis and aids in defining the progression and severity of disease. OBJECTIVE To describe… read more here.
Keywords: hla b27; frequency hla; population; b27 ... See more keywords
Distribution of human leukocyte antigen B27 (HLA-B27) in Slovak patients.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of applied biomedicine"
DOI: 10.32725/jab.2025.004
Abstract: BACKGROUND AND OBJECTIVES HLA-B27 is a genetic marker associated with spondyloarthropathies, particularly ankylosing spondylitis and axial spondyloarthritis. While its prevalence varies across populations, no data exist for Slovak patients. This study aimed to determine HLA-B27… read more here.
Keywords: age; slovak patients; positivity; hla b27 ... See more keywords