Articles with "b2r" as a keyword



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Bifunctional fusion proteins containing the sequence of the bradykinin homologue maximakinin: activities at the rat bradykinin B2 receptor.

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Published in 2018 at "Canadian journal of physiology and pharmacology"

DOI: 10.1139/cjpp-2017-0692

Abstract: To support bradykinin (BK) B2 receptor (B2R) detection and therapeutic stimulation, we developed and characterized fusion proteins consisting of the BK homolog maximakinin (MK), or variants, positioned at the C-terminus of functional proteins (enhanced green… read more here.

Keywords: fusion; microscopy; receptor; bradykinin ... See more keywords
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Bradykinin Sequestration by Plasmodium berghei Infected Erythrocytes Conditions B2R Signaling and Parasite Uptake by Fetal Trophoblasts

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Published in 2018 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2018.03106

Abstract: Plasmodium infection during pregnancy causes placental malfunction reducing fetus sustainability and leading to abortions, stillbirths, low birth weight or premature delivery. Accumulation of infected erythrocytes (IE) in the placenta is a key factor in placental… read more here.

Keywords: sequestration; b2r signaling; infected erythrocytes; berghei ... See more keywords
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Kinin B2 Receptor Activation Prevents the Evolution of Alzheimer’s Disease Pathological Characteristics in a Transgenic Mouse Model

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Published in 2020 at "Pharmaceuticals"

DOI: 10.3390/ph13100288

Abstract: Background: Alzheimer’s disease is mainly characterized by remarkable neurodegeneration in brain areas related to memory formation. This progressive neurodegeneration causes cognitive impairment, changes in behavior, functional disability, and even death. Our group has demonstrated changes… read more here.

Keywords: alzheimer disease; disease; activation; receptor ... See more keywords