Articles with "b55" as a keyword



Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia.

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Published in 2021 at "Virologica Sinica"

DOI: 10.1007/s12250-021-00414-7

Abstract: Human adenovirus type 55 (HAdV-B55) is a re-emergent acute respiratory disease pathogen that causes adult community-acquired pneumonia (CAP). Previous studies have shown that the receptor of HAdV-B14, which genome is highly similar with HAdV-B55, is… read more here.

Keywords: dsg2; hadv; human adenovirus; hadv b55 ... See more keywords

Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-21040-6

Abstract: The specific function of PP2A, a major serine/threonine phosphatase, is mediated by regulatory targeting subunits, such as members of the B55 family. Although implicated in cell division and other pathways, the specific substrates and functions… read more here.

Keywords: protein; phosphatase; replication stress; b55 ... See more keywords

Real-time Utilization of Metagenomic Sequencing in the Diagnosis and Treatment Monitoring of an Invasive Adenovirus B55 Infection and Subsequent Herpes Simplex Virus Encephalitis in an Immunocompetent Young Adult

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy114

Abstract: Abstract Background Metagenomic sequencing has shown tremendous promise in solving difficult infectious diseases cases. In this study, we utilized this technology to help guide the care of a critically ill patient with severe pneumonia, fever… read more here.

Keywords: metagenomic sequencing; treatment; encephalitis; b55 ... See more keywords

Etrinabdione (VCE-004.8), a B55α activator, promotes angiogenesis and arteriogenesis in critical limb ischemia

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Published in 2024 at "Journal of Translational Medicine"

DOI: 10.1186/s12967-024-05748-w

Abstract: Background Vasculogenic therapies explored for the treatment of peripheral artery disease (PAD) have encountered minimal success in clinical trials. Addressing this, B55α, an isoform of protein phosphatase 2A (PP2A), emerges as pivotal in vessel remodeling… read more here.

Keywords: etrinabdione; vce 004; b55; arteriogenesis ... See more keywords

PP2A-B55γ counteracts Cdk1 and regulates proper spindle orientation through the cortical dynein adaptor NuMA

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Published in 2020 at "Journal of Cell Science"

DOI: 10.1242/jcs.243857

Abstract: ABSTRACT Proper orientation of the mitotic spindle is critical for accurate development and morphogenesis. In human cells, spindle orientation is regulated by the evolutionarily conserved protein NuMA, which interacts with dynein and enriches it at… read more here.

Keywords: spindle orientation; b55; pp2a b55; t2055 ... See more keywords