Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Immunity"
DOI: 10.1016/j.immuni.2022.03.008
Abstract: Bacterial sensing by intestinal tumor cells contributes to tumor growth through cell-intrinsic activation of the calcineurin-NFAT axis, but the role of this pathway in other intestinal cells remains unclear. Here, we found that myeloid-specific deletion… read more here.
Keywords: tumor; immunity; calcineurin nfat; b7h3 b7h4 ... See more keywords
Association of B7H3 and B7H4 gene polymorphisms and protein expression with the development and prognosis of autoimmune thyroid diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical endocrinology"
DOI: 10.1111/cen.14923
Abstract: The prognosis of autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's disease (HD), varies among patients. B7‐H3 and B7‐H4, members of the B7 family of proteins, regulate immune response. To clarify the association… read more here.
Keywords: prognosis; prognosis autoimmune; b7h3 b7h4; autoimmune thyroid ... See more keywords