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BACE inhibitors in clinical development for the treatment of Alzheimer’s disease

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Published in 2018 at "Expert Review of Neurotherapeutics"

DOI: 10.1080/14737175.2018.1531706

Abstract: ABSTRACT Introduction: The amyloid hypothesis of Alzheimer’s disease (AD) affirms that brain accumulation of amyloid-β (Aβ) oligomers and soluble aggregates represent the major pathological event of the disease. Several anti-Aβ small organic molecules, monoclonal antibodies… read more here.

Keywords: bace; alzheimer disease; treatment; bace inhibitors ... See more keywords