Imbalance of the oxytocin-vasopressin system contributes to the neuropsychiatric phenotype in the BACHD mouse model of Huntington disease
Sign Up to like & getrecommendations! Published in 2020 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2020.104773
Abstract: Neuropsychiatric disturbances with altered social cognition, depression and anxiety are among the most debilitating early features in the fatal neurodegenerative disorder Huntington disease (HD) which is caused by an expanded CAG repeat in the huntingtin… read more here.
Keywords: system; huntington disease; oxytocin vasopressin; bachd mouse ... See more keywords
Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1034743
Abstract: Disturbances in sleep/wake cycles are common among patients with neurodegenerative diseases including Huntington’s disease (HD) and represent an appealing target for chrono-nutrition-based interventions. In the present work, we sought to determine whether a low-carbohydrate, high-fat… read more here.
Keywords: huntington disease; disease; bachd mouse; model ... See more keywords