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Back-to-BACs in Huntington’s disease modeling

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Published in 2022 at "Neuron"

DOI: 10.1016/j.neuron.2022.02.022

Abstract: In this issue of Neuron, Gu et al. (2022) describe a new BAC mouse model that faithfully recapitulates various aspects of Huntington's disease pathobiology and reveals important insights into the relative toxicities of mHTT-derived products. read more here.

Keywords: back bacs; disease modeling; huntington disease; bacs huntington ... See more keywords