Generating a conformational landscape of ubiquitin chains at atomistic resolution by back-mapping based sampling
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DOI: 10.3389/fchem.2022.1087963
Abstract: Ubiquitin chains are flexible multidomain proteins that have important biological functions in cellular signalling. Computational studies with all-atom molecular dynamics simulations of the conformational spaces of polyubiquitins can be challenging due to the system size… read more here.
Keywords: ubiquitin chains; back mapping; conformational landscape; based sampling ... See more keywords