The Impact of Purifying and Background Selection on the Inference of Population History: Problems and Prospects
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msab050
Abstract: Abstract Current procedures for inferring population history generally assume complete neutrality—that is, they neglect both direct selection and the effects of selection on linked sites. We here examine how the presence of direct purifying selection… read more here.
Keywords: inference population; population history; selection; background selection ... See more keywords
Background Selection Does Not Mimic the Patterns of Genetic Diversity Produced by Selective Sweeps.
Sign Up to like & getrecommendations! Published in 2020 at "Genetics"
DOI: 10.1534/genetics.120.303469
Abstract: It is increasingly evident that natural selection plays a prominent role in shaping patterns of diversity across the genome. The most commonly studied modes of natural selection are positive selection and negative selection, which refer… read more here.
Keywords: diversity; negative selection; selection; bgs ... See more keywords