Bacteria-Specific Feature Selection for Enhanced Antimicrobial Peptide Activity Predictions Using Machine-Learning Methods
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c01551
Abstract: There are several classes of short peptide molecules, known as antimicrobial peptides (AMPs), which are produced during the immune responses of living organisms against various infections. In recent years, substantial progress has been achieved in… read more here.
Keywords: specific feature; machine; bacteria specific; machine learning ... See more keywords
[11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.8b00061
Abstract: Imaging studies are frequently used to support the clinical diagnosis of infection. These techniques include computed tomography (CT) and magnetic resonance imaging (MRI) for structural information and single photon emission computed tomography (SPECT) or positron… read more here.
Keywords: bacteria specific; positron emission; para aminobenzoic; emission tomography ... See more keywords
Therapeutic nanoplatforms with bacteria-specific activation for directional transport of antibiotics.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc06398b
Abstract: An entirely new strategy is explored for directional transport delivery of antibiotics to bacteria utilizing a bacteria-activated nanoplatform. The nanoplatform can effectively prevent the premature leakage of the therapeutic payload, but release was triggered when… read more here.
Keywords: therapeutic nanoplatforms; directional transport; nanoplatforms bacteria; bacteria specific ... See more keywords
A novel radiolabelled salmochelin derivative for bacteria-specific PET imaging: synthesis, radiolabelling and evaluation.
Sign Up to like & getrecommendations! Published in 2024 at "Chemical communications"
DOI: 10.1039/d4cc00255e
Abstract: For specific imaging of bacterial infections we aimed at targeting the exclusive bacterial iron transport system via siderophore-based radiotracers. De novo synthesis and radiolabeling yielded the salmochelin-based PET radiotracer [68Ga]Ga-RMA693, which showed a favourable biodistribution… read more here.
Keywords: novel radiolabelled; radiolabelled salmochelin; synthesis; bacteria specific ... See more keywords