Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09040-0
Abstract: Neutrophils are crucial mediators of host defense that are recruited to the central nervous system (CNS) in large numbers during acute bacterial meningitis caused by Streptococcus pneumoniae. Neutrophils release neutrophil extracellular traps (NETs) during infections… read more here.
Keywords: meningitis; neutrophil extracellular; bacterial clearance; pneumococcal meningitis ... See more keywords
Survival of Patients With Vancomycin-Resistant Enterococcus faecium Bacteremia Treated With Conventional or High Doses of Daptomycin or Linezolid Is Associated With the Rate of Bacterial Clearance*
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003264
Abstract: Objectives: Vancomycin-resistant enterococci are important pathogens for healthcare-associated infections. Although linezolid is bacteriostatic and daptomycin is rapidly bactericidal against vancomycin-resistant enterococci in vitro, it is not clear whether they differ in their effect on bacterial… read more here.
Keywords: resistant enterococci; bacterial clearance; patients vancomycin; daptomycin ... See more keywords
Bacterial Clearance Is Enhanced by α2,3- and α2,6-Sialyllactose via Receptor-Mediated Endocytosis and Phagocytosis
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DOI: 10.1128/iai.00694-18
Abstract: Sialyllactose (SL) is a representative human milk oligosaccharide (HMO) of human breast milk. The roles of SL in infant brain development and immunity have been reported in previous studies. ABSTRACT Sialyllactose (SL) is a representative… read more here.
Keywords: milk; immunity; endocytosis phagocytosis; bacterial clearance ... See more keywords
Effects of Tigecycline combined with Cefoperazone on bacterial clearance and serum biochemical indexes in patients with pulmonary infections in ICU
Sign Up to like & getrecommendations! Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.38.6.5872
Abstract: Objectives: To investigate the effects of tigecycline combined with Cefoperazone on bacterial clearance and the expression of serum biochemical indexes [C-reactive protein (CRP), leukocyte count (WBC) and procalcitonin (PCT)] in patients with infection in an… read more here.
Keywords: cefoperazone; group; serum biochemical; treatment ... See more keywords
The effect of low-molecular-weight heparin combined with amikacin on the coagulation function and bacterial clearance in the treatment of patients with severe senile pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.39.1.6627
Abstract: Objective: To analyze the effect of the combined low-molecular-weight heparin (LMWH) and amikacin treatment on the bacterial clearance and changes in coagulation function in patients with severe pneumonia (SP). Methods: A single-center retrospective observational study… read more here.
Keywords: group; treatment; bacterial clearance; coagulation function ... See more keywords
CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.819554
Abstract: Cystic fibrosis (CF) human and mouse macrophages are defective in their ability to clear bacteria such as Burkholderia cenocepacia. The autophagy process in CF (F508del) macrophages is halted, and the underlying mechanism remains unclear. Furthermore,… read more here.
Keywords: cystic fibrosis; autophago lysosomes; acidification; bacterial clearance ... See more keywords
Ethanol Intoxication Impairs Respiratory Function and Bacterial Clearance and Is Associated With Neutrophil Accumulation in the Lung After Streptococcus pneumoniae Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.884719
Abstract: Alcohol consumption is commonplace in the United States and its prevalence has increased in recent years. Excessive alcohol use is linked to an increased risk of infections including pneumococcal pneumonia, mostly commonly caused by Streptococcus… read more here.
Keywords: respiratory function; infection; respiratory; bacterial clearance ... See more keywords
A Novel β-Hairpin Peptide Z-d14CFR Enhances Multidrug-Resistant Bacterial Clearance in a Murine Model of Mastitis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094617
Abstract: The widespread prevalence of antimicrobial resistance has spawned the development of novel antimicrobial agents. Antimicrobial peptides (AMPs) have gained comprehensive attention as one of the major alternatives to antibiotics. However, low antibacterial activity and high-cost… read more here.
Keywords: d14cfr; model mastitis; peptide; multidrug resistant ... See more keywords