An accurate bacterial DNA quantification assay for HTS library preparation of human biological samples
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800127
Abstract: Sequencing and classification of microbial taxa within forensically relevant biological fluids has the potential for applications in the forensic science and biomedical fields. The quantity of bacterial DNA from human samples is currently estimated based… read more here.
Keywords: bacterial dna; dna; library preparation; quantity ... See more keywords
Bacterial DNA is associated with tunnel widening in failed ACL reconstructions
Sign Up to like & getrecommendations! Published in 2019 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-019-05405-6
Abstract: PurposeTo determine if tunnel widening, defined as change in maximal tunnel diameter from the time of initial bone tunnel drilling to revision surgery is associated with bacterial deoxyribonucleic acid (DNA) presence and concentration in torn… read more here.
Keywords: bacterial dna; revision; tunnel widening; dna ... See more keywords
Bacterial profile in human atherosclerotic plaques.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.06.016
Abstract: BACKGROUND AND AIMS Several studies have confirmed the presence of bacterial DNA in atherosclerotic plaques, but its contribution to plaque stability and vulnerability is unclear. In this study, we investigated whether the bacterial plaque-profile differed… read more here.
Keywords: bacterial dna; atherosclerotic plaques; dna; symptomatic patients ... See more keywords
Ambient UV-B exposure attenuate the binding affinity of ofloxacin with bacterial DNA gyrase and induced apoptosis in human keratinocytes via Reactive Oxygen Species mediated pathway
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.088
Abstract: Ofloxacin (OFLX) is a known synthetic broad spectrum antibiotics which inhibit bacterial DNA topoisomerase activity. Previous studies showed reduced antimicrobial activity of photosensitized OFLX and its photo-products. Here, we have addressed the binding affinity of… read more here.
Keywords: reactive oxygen; bacterial dna; dna; dna gyrase ... See more keywords
Culture‐independent Characterization of the Microbiome of Healthy Pulp
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2018.03.009
Abstract: Introduction: Advances in culture‐independent molecular biotechnologies have driven a greater appreciation for the function of mutualistic microorganisms in the maintenance of states of health in humans. The purpose of this study was to test the… read more here.
Keywords: bacterial dna; culture independent; dna; healthy pulp ... See more keywords
Bacterial DNA Recognition by SERS Active Plasma-Coupled Nanogold
Sign Up to like & getrecommendations! Published in 2022 at "Nano Letters"
DOI: 10.1021/acs.nanolett.2c02835
Abstract: It is shown that surface-enhanced Raman spectroscopy (SERS) can identify bacteria based on their genomic DNA composition, acting as a “sample-distinguishing marker”. Successful spectral differentiation of bacterial species was accomplished with nanogold aggregates synthesized through… read more here.
Keywords: dna; recognition sers; dna recognition; sers active ... See more keywords
Discovery of Novel Inhibitors of Bacterial DNA Gyrase Using a QSAR-Based Approach
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04310
Abstract: Type II topoisomerases like DNA gyrase initiate ATP-dependent negative supercoils in bacterial DNA. It is critical in all of the bacteria but is missing from eukaryotes, making it a striking target for antibacterials. Ciprofloxacin is… read more here.
Keywords: bacterial dna; dna gyrase; gyrase; qsar model ... See more keywords
Presence of bacterial DNA in thrombotic material of patients with myocardial infarction
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-73011-5
Abstract: Infectious agents have been suggested to be involved in etiopathogenesis of Acute Coronary Syndrome (ACS). However, the relationship between bacterial infection and acute myocardial infarction (AMI) has not yet been completely clarified. The objective of… read more here.
Keywords: bacterial dna; dna; myocardial infarction; dna thrombotic ... See more keywords
Superstatistical model of bacterial DNA architecture
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43034
Abstract: Understanding the physical principles that govern the complex DNA structural organization as well as its mechanical and thermodynamical properties is essential for the advancement in both life sciences and genetic engineering. Recently we have discovered… read more here.
Keywords: bacterial dna; model bacterial; dna; model ... See more keywords
Circulating mitochondrial DNA and LPS-binding protein but not bacterial DNA are increased in acute HIV infection.
Sign Up to like & getrecommendations! Published in 2020 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2020.0098
Abstract: Microbial translocation has been suggested as a major driver of chronic immune activation HIV infection. Thus, we compared the extent of microbial translocation in patients with acute HIV infection and patients followed after CD4-guided structured… read more here.
Keywords: acute hiv; hiv infection; lps binding; dna ... See more keywords
Bacterial DNA promoting inflammation via the Sgk1/Nedd4L/Syk pathway in mast cells contributes to antihistamine non-responsive CSU.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad025
Abstract: Inflammation centered on non-IgE-mediated mast cell activation characterizes chronic spontaneous urticaria (CSU) resistant to non-sedating H1-antihistamines (nsAH). We recently uncovered a strong positive association between inflammation and the fecal Escherichia. To further explore the actions… read more here.
Keywords: inflammation; mast; btdna; bacterial dna ... See more keywords