Bacterial Hsp90 predominantly buffers but does not potentiate the phenotypic effects of deleterious mutations during fluorescent protein evolution.
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DOI: 10.1093/genetics/iyac154
Abstract: Chaperones facilitate the folding of other ("client") proteins, and can thus affect the adaptive evolution of these clients. Specifically, chaperones affect the phenotype of proteins via two opposing mechanisms. On the one hand, they can… read more here.
Keywords: hsp90; fluorescent protein; evolution; phenotypic effects ... See more keywords